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Cycloguanil hydrochloride
CAS No. 152-53-4
Cycloguanil hydrochloride( Chloroguanide Triazine )
Catalog No. M20150 CAS No. 152-53-4
Cycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 46 | In Stock |
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| 5MG | 69 | In Stock |
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| 10MG | 113 | In Stock |
|
| 25MG | 186 | In Stock |
|
| 50MG | 332 | In Stock |
|
| 100MG | 494 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCycloguanil hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionCycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms respectively).
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DescriptionCycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms respectively).
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SynonymsChloroguanide Triazine
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PathwayMicrobiology/Virology
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TargetParasite
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RecptorParasite
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Research Area——
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Indication——
Chemical Information
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CAS Number152-53-4
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Formula Weight288.18
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Molecular FormulaC11H14ClN5.ClH
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Purity>98% (HPLC)
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SolubilityDMSO: 20 mg/mL (69.4 mM);Water: 5 mg/mL (17.35 mM)
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SMILESCl.CC1(C)N=C(N)N=C(N)N1c1ccc(Cl)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Wright JD et al. The role of S-mephenytoin hydroxylase (CYP2C19) in the metabolism of the antimalarial biguanides. Br J Clin Pharmacol. 1995 Apr;39(4):441-4.
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